Water → N-(3-Cyano-4-neopentyloxyphenyl)-1-(4-fluorophenyl)-5-methylpyrazole-3-carboxamide

HRID 808496Notes

Reaction equation

HRID 808496 reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]([C:14](=[O:15])[OH:16])[cH:11][c:12]2[CH3:13])[cH:6][cH:7]1.[NH2:17][c:18]1[cH:19][cH:20][c:21]([O:26][CH2:27][C:28]([CH3:29])([CH3:30])[CH3:31])[c:22]([C:23]#[N:24])[cH:25]1.[OH2:49].[P:39]([C:40]#[N:41])([O:42][CH2:43][CH3:44])([O:45][CH2:46][CH3:47])=[O:48]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]([C:14](=[O:16])[NH:17][c:18]3[cH:19][cH:20][c:21]([O:26][CH2:27][C:28]([CH3:29])([CH3:30])[CH3:31])[c:22]([C:23]#[N:24])[cH:25]3)[cH:11][c:12]2[CH3:13])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 76257Diethyl cyanophosphonateHCID 178227345-Amino-2-neopentyloxybenzonitrileHCID 222279451-(4-fluorophenyl)-5-methyl-1H-pyrazole-3-carboxylic acid

Product 1

HCID 22227973N-(3-Cyano-4-neopentyloxyphenyl)-1-(4-fluorophenyl)-5-methylpyrazole-3-carboxamide

Sources & evidence

ORD record
ord-787ed8e1d51a48a6ac10d1d45a2f8a8c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…