Dimethyl Sulfide → 4-[3-bromo-2-(3,5-dimethylisoxazol-4-yl)-1H-indole-1-yl]phenol

HRID 810100Notes

Reaction equation

HRID 810100 reaction equation
[B:4]([F:5])([F:6])[F:7].[Br:8][c:9]1[c:10](-[c:26]2[c:27]([CH3:32])[n:28][o:29][c:30]2[CH3:31])[n:11](-[c:18]2[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]2)[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]12.[CH3:1][S:2][CH3:3].[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[Cl:33][CH2:34][Cl:35]>>[Br:8][c:9]1[c:10](-[c:26]2[c:27]([CH3:32])[n:28][o:29][c:30]2[CH3:31])[n:11](-[c:18]2[cH:19][cH:20][c:21]([OH:24])[cH:22][cH:23]2)[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]12

Participants

6

Reactant 5

HCID 1068Dimethyl SulfideHCID 6344DichloromethaneHCID 6356Boron trifluorideHCID 8857Ethyl AcetateHCID 583782244-(3-bromo-1-(4-methoxyphenyl)-1H-indol-2-yl)-3,5-dimethylisoxazole

Product 1

HCID 444663574-[3-bromo-2-(3,5-dimethylisoxazol-4-yl)-1H-indole-1-yl]phenol

Sources & evidence

ORD record
ord-259f14f8eeaa4eceae06ecd05628ea7f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…