HRID810444

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID6344

Dichloromethane

CH2Cl2

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID66836

3-Bromo-4-methoxybenzoic acid

C8H7BrO3

HCID10879216

6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine

C15H17N3

PRODUCTS

生成物

结构：COc1ccc(C(=O)Nc2cnc3c(c2)CN(Cc2ccccc2)CC3)cc1Br

HCID21196391

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-485918bda2694edd8e6d3b2b39f416bc
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1[O:11][CH3:12].[CH3:14][N:15]([CH3:16])[CH2:17][CH2:18][CH2:19][N:20]=[C:21]=[N:22][CH2:23][CH3:24].[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[Cl:48][CH2:49][Cl:50].[ClH:13].[NH2:25][c:26]1[cH:27][n:28][c:29]2[c:34]([cH:35]1)[CH2:33][N:32]([CH2:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)[CH2:31][CH2:30]2>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:7])[NH:25][c:26]2[cH:27][n:28][c:29]3[c:34]([cH:35]2)[CH2:33][N:32]([CH2:36][c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[CH2:31][CH2:30]3)[cH:8][cH:9][c:10]1[O:11][CH3:12]