Acetate → Methyl 6-(6,7-dimethoxyquinolin-4-yloxy)benzofuran-3-carboxylate
Reaction equation
[C:77]([O-:78])(=[O:79])[CH3:80].[C:82]([O-:83])(=[O:84])[CH3:85].[CH3:72][N:73]([CH3:74])[CH:75]=[O:76].[CH:30]1([P:31]([CH:32]2[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2-[c:44]2[c:45]([CH:46]([CH3:47])[CH3:48])[cH:49][c:50]([CH:51]([CH3:52])[CH3:53])[cH:54][c:55]2[CH:56]([CH3:57])[CH3:58])[CH2:59][CH2:60][CH2:61][CH2:62][CH2:63]1.[Cl:15][c:16]1[cH:17][cH:18][n:19][c:20]2[cH:21][c:22]([O:28][CH3:29])[c:23]([O:26][CH3:27])[cH:24][c:25]12.[K+:69].[K+:70].[K+:71].[OH:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([C:9](=[O:10])[O:11][CH3:12])[cH:7][o:8]2)[cH:13][cH:14]1.[P:64]([O-:65])([O-:66])([O-:67])=[O:68].[Pd+2:81]>>[O:1]([c:2]1[cH:3][c:4]2[c:5]([c:6]([C:9](=[O:10])[O:11][CH3:12])[cH:7][o:8]2)[cH:13][cH:14]1)[c:16]1[cH:17][cH:18][n:19][c:20]2[cH:21][c:22]([O:28][CH3:29])[c:23]([O:26][CH3:27])[cH:24][c:25]12Participants
9
Reactant 8
HCID 175Acetate2×
HCID 813Potassium Cation3×
HCID 1061Phosphate
HCID 6228Dimethylformamide
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 4596104-Chloro-6,7-dimethoxyquinoline
HCID 111557942-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenyl
HCID 59577559Methyl 6-hydroxybenzofuran-3-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-48c109707da248b488aeceb160e48e19
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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