HRID813386

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

2 次

HCID674

Dimethylamine

C2H7N

HCID962

Water

H2O

HCID6344

Dichloromethane

CH2Cl2

HCID7972

4-Methylmorpholine

C5H11NO

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

反应SMILES：Cc1cc(C(=O)O)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1

HCID57736439

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1cc(C(=O)N(C)C)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1

HCID57736490

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-6e4bb55cec8949e6b74c5d13dbdcfb6c
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[CH2:52]([N:53]=[C:54]=[N:55][CH2:56][CH2:57][CH2:58][N:59]([CH3:60])[CH3:61])[CH3:62].[CH2:63]([Cl:64])[Cl:65].[CH3:31][NH:32][CH3:33].[CH3:44][N:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1.[ClH:30].[ClH:51].[F:1][c:2]1[c:3]([CH:9]([c:10]2[c:11]([CH3:19])[cH:12][c:13]([C:16](=[O:17])[OH:18])[n:14][cH:15]2)[S:20](=[O:21])(=[O:22])[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[OH2:66].[OH:34][n:35]1[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[n:42][n:43]1>>[F:1][c:2]1[c:3]([CH:9]([c:10]2[c:11]([CH3:19])[cH:12][c:13]([C:16](=[O:17])[N:32]([CH3:31])[CH3:33])[n:14][cH:15]2)[S:20](=[O:21])(=[O:22])[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1