Water → Methyl 4-(3-chloro-4-(((methylamino) carbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxylate

HRID 814790Notes

Reaction equation

HRID 814790 reaction equation
[CH3:35][NH2:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[Cl:1][c:2]1[c:3]([NH:25][C:26]([O:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)=[O:34])[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:23][CH3:24])[c:16]([C:19](=[O:20])[O:21][CH3:22])[cH:17][c:18]23)[cH:7]1.[OH2:43]>>[Cl:1][c:2]1[c:3]([NH:25][C:26](=[O:34])[NH:36][CH3:35])[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:23][CH3:24])[c:16]([C:19](=[O:20])[O:21][CH3:22])[cH:17][c:18]23)[cH:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 6329MethylamineHCID 8857Ethyl AcetateHCID 22936324Phenyl N-(2-chloro-4-(7-methoxy-6-methoxycarbonyl-4-quinolyl)oxyphenyl)carbamate

Product 1

HCID 22936945Methyl 4-(3-chloro-4-(((methylamino) carbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxylate

Sources & evidence

ORD record
ord-a2888d5c0f1943d59cb069b6c4b57fbb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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