Hydrochloric Acid → 7,8-Difluoro-5-iodochroman-6-ol
Reaction equation
[C:24]([O:25][CH3:26])([CH3:27])([CH3:28])[CH3:29].[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[ClH:1].[F:2][c:3]1[c:4]([O:15][CH2:16][O:17][CH3:18])[c:5]([I:14])[c:6]2[c:11]([c:12]1[F:13])[O:10][CH2:9][CH2:8][CH2:7]2>>[F:2][c:3]1[c:4]([OH:15])[c:5]([I:14])[c:6]2[c:11]([c:12]1[F:13])[O:10][CH2:9][CH2:8][CH2:7]2Participants
5
Sources & evidence
- ORD record
- ord-bb21ef4892264168ac152e42851c1cb9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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