Triethylamine → 1-Mesyl-4-(3-methylphenyl)but-3-yne

HRID 818671Notes

Reaction equation

HRID 818671 reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[Cu:24][I:25].[I:9][c:10]1[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]1.[Pd:26]([Cl:27])[Cl:28].[S:1](=[O:2])(=[O:3])([CH3:4])[CH2:5][CH2:6][C:7]#[CH:8].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[S:1](=[O:2])(=[O:3])([CH3:4])[CH2:5][CH2:6][C:7]#[C:8][c:10]1[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]1

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 122683-IodotolueneHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 12053774192989-95-0

Product 1

HCID 184279601-Mesyl-4-(3-methylphenyl)but-3-yne

Sources & evidence

ORD record
ord-317dec8a42134c058b2b28ad1e860dfa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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