1-Chloro-4-nitrobenzene → 1-Methyl-4-(4-nitrophenyl)piperazine

HRID 820392Notes

Reaction equation

HRID 820392 reaction equation
[CH2:18]([N:19]([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[CH3:26].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:11][N:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1>>[c:2]1([N:15]2[CH2:14][CH2:13][N:12]([CH3:11])[CH2:17][CH2:16]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 74741-Chloro-4-nitrobenzeneHCID 8028TetrahydrofuranHCID 531671-MethylpiperazineHCID 81531Diisopropylethylamine

Product 1

HCID 28251981-Methyl-4-(4-nitrophenyl)piperazine

Sources & evidence

ORD record
ord-c5aacf74b5c34684bb78640a6ace1f2d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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