Water → tert-Butyl 2-cyanopyrrolidine-1-carboxylate

HRID 820415Notes

Reaction equation

HRID 820415 reaction equation
[C:14](=[O:15])([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[N:21]1[CH:22]([C:23](=[O:24])[NH-:25])[CH2:26][CH2:27][CH2:28]1.[CH2:29]([N:30]([CH2:31][CH3:32])[CH2:33][CH3:34])[CH3:35].[F:1][C:2]([F:3])([F:4])[C:5]([O:6][C:7](=[O:8])[C:9]([F:10])([F:11])[F:12])=[O:13].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[OH2:36]>>[C:14](=[O:15])([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[N:21]1[CH:22]([C:23]#[N:25])[CH2:26][CH2:27][CH2:28]1

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 9845Trifluoroacetic anhydrideHCID 178451695HCID 178451695, compound

Product 1

HCID 2756786tert-Butyl 2-cyanopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-1f27b921dfb541679772935a1c446b7d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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