Methane → Hydrochloric Acid

HRID 820676Notes

Reaction equation

HRID 820676 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([F:15])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1.[C:24].[CH3:17][OH:18].[ClH:16].[O:19]1[CH2:20][CH2:21][CH2:22][CH2:23]1.[Pd:25]>>[CH2:1]([NH2:2])[c:3]1[cH:4][c:5]([F:15])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1.[ClH:16]

Participants

8

Reactant 6

HCID 297MethaneHCID 313Hydrochloric AcidHCID 887MethanolHCID 8028TetrahydrofuranHCID 23938PalladiumHCID 21097536N-(4-cyano-2,6-difluorophenyl)methanesulfonamide

Product 2

HCID 313Hydrochloric AcidHCID 21097524N-(4-Aminomethyl-2,6-difluoro-phenyl)-methanesulfonamide

Sources & evidence

ORD record
ord-1abde1a5f58a46b584619d28258a1edb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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