Ammonium → 4-(1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorobenzenamine

HRID 821007Notes

Reaction equation

HRID 821007 reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][cH:10][c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:27])[cH:20][c:21]([N+:24]([O-:25])=[O:26])[cH:22][cH:23]2)[cH:28][cH:29]1.[CH3:30][OH:31].[Cl-:32].[ClH:34].[NH4+:33].[Zn:35]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][cH:10][c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:27])[cH:20][c:21]([NH2:24])[cH:22][cH:23]2)[cH:28][cH:29]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 313Hydrochloric AcidHCID 887MethanolHCID 8028TetrahydrofuranHCID 23994ZincHCID 672207711-(4-methoxybenzyl)-4-(2-fluoro-4-nitrophenoxy)-1H-pyrazolo[3,4-b]pyridine

Product 1

HCID 685158574-(1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorobenzenamine

Sources & evidence

ORD record
ord-056d1884930749d791785bc78b1159ec
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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