Diethyl Ether → 5-Hydroxymethyl-2,4-dimethoxy-benzonitrile

HRID 822360Notes

Reaction equation

[Br:1][c:2]1[c:3]([O:12][CH3:13])[cH:4][c:5]([O:10][CH3:11])[c:6]([CH2:8][OH:9])[cH:7]1.[C-:24]#[N:25].[C-:27]#[N:28].[CH3:14][N:15]([CH3:16])[CH:17]=[O:18].[CH3:19][CH2:20][O:21][CH2:22][CH3:23].[Zn+2:26].[cH:29]1[cH:30][cH:31][c:32]([P:33]([Pd:34]([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105]1>>[c:2]1([C:14]#[N:15])[c:3]([O:12][CH3:13])[cH:4][c:5]([O:10][CH3:11])[c:6]([CH2:8][OH:9])[cH:7]1