Tetrahydrofuran → 4-(4-Bromo-2-trifluoromethyl-benzenesulfonyl)-morpholine

HRID 823746Notes

Reaction equation

HRID 823746 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:12]([F:13])([F:14])[F:15])[c:5]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:6][cH:7]1.[CH2:16]1[CH2:17][O:18][CH2:19][CH2:20][NH:21]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][CH2:30][O:31][C:32](=[O:33])[CH3:34]>>[Br:1][c:2]1[cH:3][c:4]([C:12]([F:13])([F:14])[F:15])[c:5]([S:8](=[O:9])(=[O:10])[N:21]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8083MorpholineHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 27786084-Bromo-2-(trifluoromethyl)benzenesulfonyl chloride

Product 1

HCID 473151804-(4-Bromo-2-trifluoromethyl-benzenesulfonyl)-morpholine

Sources & evidence

ORD record
ord-9a3fa4f2aebd449ca8e5a68a9bea4aa3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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