Diisopropylamine → Methyl 2-[4-[3-[4-[3-(4-hydroxypiperidin-1-yl)prop-1-ynyl]phenyl]-3-[4-(trifluoromethylsulfanyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetate

HRID 823888Notes

Reaction equation

[CH2:1]([C:2]#[CH:3])[N:4]1[CH2:5][CH2:6][CH:7]([OH:10])[CH2:8][CH2:9]1.[CH:46]([NH:47][CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[Cu:58][I:59].[I:11][c:12]1[cH:13][cH:14][c:15]([C:18](=[CH:19][CH2:20][O:21][c:22]2[cH:23][c:24]([CH3:34])[c:25]([O:26][CH2:27][C:28](=[O:29])[O:30][CH3:31])[cH:32][cH:33]2)[c:35]2[cH:36][cH:37][c:38]([S:41][C:42]([F:43])([F:44])[F:45])[cH:39][cH:40]2)[cH:16][cH:17]1.[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1.[Pd:60]([Cl:61])[Cl:62].[c:63]1([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[cH:77][cH:78][cH:79][cH:80][cH:81]1.[c:82]1([P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[cH:96][cH:97][cH:98][cH:99][cH:100]1>>[CH2:1]([C:2]#[C:3][c:12]1[cH:13][cH:14][c:15]([C:18](=[CH:19][CH2:20][O:21][c:22]2[cH:23][c:24]([CH3:34])[c:25]([O:26][CH2:27][C:28](=[O:29])[O:30][CH3:31])[cH:32][cH:33]2)[c:35]2[cH:36][cH:37][c:38]([S:41][C:42]([F:43])([F:44])[F:45])[cH:39][cH:40]2)[cH:16][cH:17]1)[N:4]1[CH2:5][CH2:6][CH:7]([OH:10])[CH2:8][CH2:9]1