Potassium Cation → 4-(5-Fluoro-indazol-2-yl)-phenol

HRID 824100Notes

Reaction equation

HRID 824100 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][cH:7]1.[CH3:27][N:28]([CH3:29])[CH2:30][CH2:31][NH2:32].[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[Cu:33][I:34].[F:9][c:10]1[cH:11][c:12]2[cH:13][n:14][nH:15][c:16]2[cH:17][cH:18]1.[K+:24].[K+:25].[K+:26].[P:19]([O-:20])([O-:21])([O-:22])=[O:23]>>[c:2]1(-[n:14]2[cH:13][c:12]3[cH:11][c:10]([F:9])[cH:18][cH:17][c:16]3[n:15]2)[cH:3][cH:4][c:5]([OH:8])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 1140TolueneHCID 78084-BromophenolHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66053N,N-DimethylethylenediamineHCID 178424865-Fluoro-1H-indazole

Product 1

HCID 681576274-(5-Fluoro-indazol-2-yl)-phenol

Sources & evidence

ORD record
ord-27fda865229949ddbcba0cb8930fd17b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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