HRID824136

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID24813

Phosphoric trichloride

Cl3OP

结构：CC(C)Oc1cc(C(NC=O)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F

HCID86613065

未命名化合物

PRODUCTS

生成物

结构：[C-]#[N+]C(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(F)c(OC(C)C)c1

HCID59459265

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-13a2c31e28554ecc9c900c71eaa06f5f
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[F:1][c:2]1[c:3]([O:26][CH:27]([CH3:28])[CH3:29])[cH:4][c:5]([CH:8]([NH:9][CH:10]=[O:11])[c:12]2[cH:13][c:14]([F:25])[cH:15][c:16]([O:18][C:19]([CH:20]([F:21])[F:22])([F:23])[F:24])[cH:17]2)[cH:6][cH:7]1.[OH2:47].[P:37]([Cl:38])([Cl:39])([Cl:40])=[O:41]>>[F:1][c:2]1[c:3]([O:26][CH:27]([CH3:28])[CH3:29])[cH:4][c:5]([CH:8]([N+:9]#[C-:10])[c:12]2[cH:13][c:14]([F:25])[cH:15][c:16]([O:18][C:19]([CH:20]([F:21])[F:22])([F:23])[F:24])[cH:17]2)[cH:6][cH:7]1