Chloride → 1-(2-Chloropyrimidin-4-yl)ethanone

HRID 824728Notes

Reaction equation

HRID 824728 reaction equation
[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1.[CH3:15][Mg+:16].[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[Cl-:14].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[N:10]([O:11][CH3:12])[CH3:13])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[CH3:15])[n:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 772313502-chloro-N-methoxy-N-methylpyrimidine-4-carboxamideHCID 178477777HCID 178477777, compound

Product 1

HCID 446138781-(2-Chloropyrimidin-4-yl)ethanone

Sources & evidence

ORD record
ord-01cc01ff0a6d46e88683fe43b429e61c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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