Dimethylformamide → 2-(2-Acetylaminopyridin-4-ylmethylthio)-N-(3,5-dimethylphenyl)pyridine-3-carboxamide

HRID 824852Notes

Reaction equation

HRID 824852 reaction equation
[C:19]([CH3:20])(=[O:21])[NH:22][c:23]1[n:24][cH:25][cH:26][c:27]([CH2:29][O:30][S:31]([CH3:32])(=[O:33])=[O:34])[cH:28]1.[CH3:1][c:2]1[cH:3][c:4]([NH:9][C:10](=[O:11])[c:12]2[c:13](=[S:18])[nH:14][cH:15][cH:16][cH:17]2)[cH:5][c:6]([CH3:8])[cH:7]1.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[CH3:48][N:49]([CH3:50])[CH:51]=[O:52]>>[CH3:1][c:2]1[cH:3][c:4]([NH:9][C:10](=[O:11])[c:12]2[c:13]([S:18][CH2:29][c:27]3[cH:26][cH:25][n:24][c:23]([NH:22][C:19]([CH3:20])=[O:21])[cH:28]3)[n:14][cH:15][cH:16][cH:17]2)[cH:5][c:6]([CH3:8])[cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 231510342-Acetylamino-4-methanesulfonyloxymethylpyridineHCID 23151038N-(3,5-Dimethylphenyl)-2-thioxo-1,2-dihydropyridine-3-carboxamide

Product 1

HCID 111889642-(2-Acetylaminopyridin-4-ylmethylthio)-N-(3,5-dimethylphenyl)pyridine-3-carboxamide

Sources & evidence

ORD record
ord-d3848aad543f4dc88e1eaf8a2e99a536
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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