Hydrochloric Acid → Tert-butyl 3-(4-bromophenyl)-2,2-dimethylpropionate

HRID 825657Notes

Reaction equation

HRID 825657 reaction equation
[Br:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][Br:25])[cH:26][cH:27]1.[CH3:9][CH:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH3:18].[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[ClH:28].[Li+:8].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[CH3:9][C:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])([CH3:18])[CH2:24][c:23]1[cH:22][cH:21][c:20]([Br:19])[cH:27][cH:26]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 685274-Bromobenzyl bromideHCID 519334Tert-butyl 2-methylpropanoateHCID 5062348Diisopropylamide

Product 1

HCID 22708227Tert-butyl 3-(4-bromophenyl)-2,2-dimethylpropionate

Sources & evidence

ORD record
ord-1f4fca61e71a49a7a3a8248dbc406445
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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