Hydrochloric Acid → 2-(2,4-difluorophenyl)-6-(2-methylpyrimidin-5-yl)-N-[1-[1-oxido-6-(trifluoromethyl)pyridin-1-ium-3-yl]ethyl]pyridine-4-carboxamide
Reaction equation
[CH:64]([N:65]([CH:66]([CH3:67])[CH3:68])[CH2:69][CH3:70])([CH3:71])[CH3:72].[ClH:25].[F:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][c:16](-[c:18]3[cH:19][n:20][c:21]([CH3:24])[n:22][cH:23]3)[n:17]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[O-:26][n+:27]1[cH:28][c:29]([CH:37]([CH3:38])[NH2:39])[cH:30][cH:31][c:32]1[C:33]([F:34])([F:35])[F:36].[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[P-:40]([F:41])([F:42])([F:43])([F:44])([F:45])[F:46].[n:47]1([O:48][C:49]([N:50]([CH3:51])[CH3:52])=[N+:53]([CH3:54])[CH3:55])[c:56]2[n:57][cH:58][cH:59][cH:60][c:61]2[n:62][n:63]1>>[F:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]([C:12](=[O:14])[NH:39][CH:37]([c:29]3[cH:28][n+:27]([O-:26])[c:32]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:30]3)[CH3:38])[cH:15][c:16](-[c:18]3[cH:19][n:20][c:21]([CH3:24])[n:22][cH:23]3)[n:17]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
8
Reactant 7
HCID 313Hydrochloric Acid
HCID 6228Dimethylformamide
HCID 9886Hexafluorophosphate
HCID 81531Diisopropylethylamine
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 66697576HCID 66697576, compound
HCID 673390222-(2,4-Difluorophenyl)-6-(2-methylpyrimidin-5-yl)isonicotinic acidProduct 1
Sources & evidence
- ORD record
- ord-09cc6c5fecec4bf89ec608f788bb2d95
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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