Anthranilic Acid → 7-(2-amino-benzoylamino)-4,4-dimethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester

HRID 829737Notes

Reaction equation

[B-:31]([F:32])([F:33])([F:34])[F:35].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([NH2:20])[cH:13][cH:14][c:15]2[C:16]([CH3:18])([CH3:19])[CH2:17]1.[CH3:67][CH2:68][O:69][C:70]([CH3:71])=[O:72].[CH:53]([N:54]([CH2:55][CH3:56])[CH:57]([CH3:58])[CH3:59])([CH3:60])[CH3:61].[NH2:21][c:22]1[c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28][cH:29][cH:30]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[OH2:73].[n:36]1([O:37][C:38]([N:39]([CH3:40])[CH3:41])=[N+:42]([CH3:43])[CH3:44])[c:45]2[cH:46][cH:47][cH:48][cH:49][c:50]2[n:51][n:52]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([NH:20][C:24]([c:23]3[c:22]([NH2:21])[cH:30][cH:29][cH:28][cH:27]3)=[O:25])[cH:13][cH:14][c:15]2[C:16]([CH3:18])([CH3:19])[CH2:17]1