Chloroform → 5-(Pyrrolidin-1-ylsulfonyl)indoline-2,3-dione

HRID 830115Notes

Reaction equation

HRID 830115 reaction equation
[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1.[CH2:21]1[CH2:22][CH2:23][NH:24][CH2:25]1.[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[CH:35]([Cl:36])([Cl:37])[Cl:38].[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][c:7]([S:12](=[O:13])(=[O:14])[Cl:15])[cH:8][c:9]2[C:10]1=[O:11]>>[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][c:7]([S:12](=[O:13])(=[O:14])[N:24]3[CH2:23][CH2:22][CH2:21][CH2:25]3)[cH:8][c:9]2[C:10]1=[O:11]

Participants

6

Reactant 5

HCID 6212ChloroformHCID 8028TetrahydrofuranHCID 31268PyrrolidineHCID 81531DiisopropylethylamineHCID 159089472,3-Dioxoindoline-5-sulfonyl chloride

Product 1

HCID 41173815-(Pyrrolidin-1-ylsulfonyl)indoline-2,3-dione

Sources & evidence

ORD record
ord-44fb1372ba01498a8115994ed5cd7871
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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