Hydrochloric Acid → N-(2-(5-chloro-1H-indol-3-yl)ethyl)-1-(3-fluoro-4-(trifluoromethyl)phenyl)-2-oxopyrrolidine-3-carboxamide
Reaction equation
[CH:59]([N:60]([CH2:61][CH3:62])[CH:63]([CH3:64])[CH3:65])([CH3:66])[CH3:67].[Cl:2][c:3]1[cH:4][c:5]2[c:6]([CH2:12][CH2:13][NH2:14])[cH:7][nH:8][c:9]2[cH:10][cH:11]1.[ClH:1].[F:15][c:16]1[cH:17][c:18]([N:26]2[C:27](=[O:34])[CH:28]([C:31](=[O:32])[OH:33])[CH2:29][CH2:30]2)[cH:19][cH:20][c:21]1[C:22]([F:23])([F:24])[F:25].[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[P-:35]([F:36])([F:37])([F:38])([F:39])([F:40])[F:41].[n:42]1([O:43][C:44]([N:45]([CH3:46])[CH3:47])=[N+:48]([CH3:49])[CH3:50])[c:51]2[n:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[Cl:2][c:3]1[cH:4][c:5]2[c:6]([CH2:12][CH2:13][NH:14][C:31]([CH:28]3[C:27](=[O:34])[N:26]([c:18]4[cH:17][c:16]([F:15])[c:21]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:19]4)[CH2:30][CH2:29]3)=[O:32])[cH:7][nH:8][c:9]2[cH:10][cH:11]1Participants
8
Reactant 7
HCID 313Hydrochloric Acid
HCID 6228Dimethylformamide
HCID 9886Hexafluorophosphate
HCID 773795-Chlorotryptamine
HCID 81531Diisopropylethylamine
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 668321321-(3-Fluoro-4-(trifluoromethyl)phenyl)-2-oxopyrrolidine-3-carboxylic acidProduct 1
Sources & evidence
- ORD record
- ord-e9196a86c8094cda9bba6bf2b426cc8b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…