Dichloromethane → Benzyl 4-Hydroxy-1-piperidinecarboxylate

HRID 831014Notes

Reaction equation

HRID 831014 reaction equation
[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:26][CH2:27][Cl:28].[Cl:8][C:9](=[O:10])[O:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:9](=[O:10])[O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 79341Piperidin-4-ol

Product 1

HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-f807a88f07bb4976a9493583716a5d49
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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