4-Methylmorpholine → N-[4-[(3-bromophenyl)amino]-3-cyano-7-methoxy-6-quinolinyl]-2-butynamide
Reaction equation
[C:1]([C:2]#[C:3][CH3:4])(=[O:5])[OH:6].[CH3:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1.[Cl:7][C:8]([O:9][CH2:10][CH:11]([CH3:12])[CH3:13])=[O:14].[NH2:22][c:23]1[cH:24][c:25]2[c:26]([NH:37][c:38]3[cH:39][c:40]([Br:44])[cH:41][cH:42][cH:43]3)[c:27]([C:35]#[N:36])[cH:28][n:29][c:30]2[cH:31][c:32]1[O:33][CH3:34].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[C:1]([C:2]#[C:3][CH3:4])(=[O:6])[NH:22][c:23]1[cH:24][c:25]2[c:26]([NH:37][c:38]3[cH:39][c:40]([Br:44])[cH:41][cH:42][cH:43]3)[c:27]([C:35]#[N:36])[cH:28][n:29][c:30]2[cH:31][c:32]1[O:33][CH3:34]Participants
6
Sources & evidence
- ORD record
- ord-2b70846dfc794416a2b799d0a81d3d64
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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