Tetrahydrofuran → N-Methyltyramine

HRID 831501Notes

Reaction equation

HRID 831501 reaction equation
[Al+3:16].[CH3:1][O:2][C:3]([NH:4][CH2:5][CH2:6][c:7]1[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]1)=[O:14].[H-:15].[H-:18].[H-:19].[H-:20].[Li+:17].[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1>>[CH3:3][NH:4][CH2:5][CH2:6][c:7]1[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 20596424Methyl [2-(4-hydroxyphenyl)ethyl]carbamate

Product 1

HCID 9727N-Methyltyramine

Sources & evidence

ORD record
ord-1a26c19a19214314908393db0208fefa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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