Tetrahydrofuran → Benzyl 3,3-dimethyl-2-oxopyrrolidine-1-carboxylate

HRID 833826Notes

Reaction equation

HRID 833826 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][C:2]1([CH3:8])[C:3](=[O:7])[NH:4][CH2:5][CH2:6]1.[CH3:9][Si:10]([CH3:11])([CH3:12])[N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17].[Cl:19][C:20](=[O:21])[O:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[Li+:18]>>[CH3:1][C:2]1([CH3:8])[C:3](=[O:7])[N:4]([C:20](=[O:21])[O:22][CH2:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 10387Benzyl chloroformateHCID 28486Lithium ionHCID 3280088Npc316347HCID 51149083,3-Dimethylpyrrolidin-2-one

Product 1

HCID 57878089Benzyl 3,3-dimethyl-2-oxopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-e890a49770c8454d91b21bc4afadcdca
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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