Benzaldehyde → Ethyl 4-(alpha-hydroxybenzyl)benzoate

HRID 833844Notes

Reaction equation

HRID 833844 reaction equation
[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:33][O:34][C:35]([CH3:36])([CH3:37])[CH3:38].[CH:13]([Mg:14][CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[CH:20](=[O:21])[c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[I:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1>>[c:2]1([CH:20]([OH:21])[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 240BenzaldehydeHCID 8028TetrahydrofuranHCID 15413tert-Butyl methyl etherHCID 142891Ethyl 4-iodobenzoateHCID 178461729HCID 178461729, compound

Product 1

HCID 10244131Ethyl 4-(alpha-hydroxybenzyl)benzoate

Sources & evidence

ORD record
ord-f5c701d673b647d29584cbd02de21ac2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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