Chloride → (2-Bromo-5-iodo-phenyl)-chroman-6-yl-methanone

HRID 834103Notes

Reaction equation

HRID 834103 reaction equation
[Al+3:29].[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([I:11])[cH:9][cH:10]1.[Cl-:28].[Cl-:30].[Cl-:31].[Cl:12][C:13]([C:14]([Cl:15])=[O:16])=[O:17].[Cl:32][CH2:33][Cl:34].[O:18]1[CH2:19][CH2:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]21.[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[Br:1][c:2]1[c:3]([C:4](=[O:6])[c:24]2[cH:23][c:22]3[c:27]([cH:26][cH:25]2)[O:18][CH2:19][CH2:20][CH2:21]3)[cH:7][c:8]([I:11])[cH:9][cH:10]1

Participants

8

Reactant 7

HCID 312Chloride3×HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 104727Aluminum CationHCID 136319ChromanHCID 27355722-Bromo-5-iodobenzoic acid

Product 1

HCID 58340801(2-Bromo-5-iodo-phenyl)-chroman-6-yl-methanone

Sources & evidence

ORD record
ord-80f5c9f338264d5f90aef5c9366ce818
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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