Hydrochloric Acid → Methyl 3,4-dihydro-2H-1,4-benzoxazine-5-carboxylate

HRID 834568Notes

Reaction equation

HRID 834568 reaction equation
[BH4-:16].[C:19](=[O:20])([O-:21])[O-:22].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[c:10]1[NH:11][C:12](=[O:15])[CH2:13][O:14]2.[CH3:30][CH2:31][O:32][C:33]([CH3:34])=[O:35].[ClH:18].[Na+:17].[Na+:23].[Na+:24]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[c:10]1[NH:11][CH2:12][CH2:13][O:14]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ion3×HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 28123BorohydrideHCID 59153381HCID 59153381, compound

Product 1

HCID 14373654Methyl 3,4-dihydro-2H-1,4-benzoxazine-5-carboxylate

Sources & evidence

ORD record
ord-d6ed601d1e6a46ad9e114ce83e117949
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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