Tetrahydrofuran → N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-2-(pyridin-2-ylmethoxy)pyrimidine-5-carboxamide

HRID 835306Notes

Reaction equation

[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:9][Si:10]([CH3:11])([CH3:12])[N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17].[CH:19]1([NH:22][C:23](=[O:24])[c:25]2[cH:26][cH:27][c:28]([CH3:44])[c:29]([NH:31][C:32](=[O:33])[c:34]3[cH:35][n:36][c:37]([S:40]([CH3:41])(=[O:42])=[O:43])[n:38][cH:39]3)[cH:30]2)[CH2:20][CH2:21]1.[Li+:18].[n:1]1[c:2]([CH2:7][OH:8])[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH2:7][O:8][c:37]2[n:36][cH:35][c:34]([C:32]([NH:31][c:29]3[c:28]([CH3:44])[cH:27][cH:26][c:25]([C:23]([NH:22][CH:19]4[CH2:20][CH2:21]4)=[O:24])[cH:30]3)=[O:33])[cH:39][n:38]2)[cH:3][cH:4][cH:5][cH:6]1