Tetrahydrofuran → HCID 52951670, compound

HRID 836004Notes

Reaction equation

HRID 836004 reaction equation
[CH3:25][Si:26]([N-:27][Si:28]([CH3:29])([CH3:30])[CH3:31])([CH3:32])[CH3:33].[CH3:35][N:36]1[CH2:37][CH2:38][CH2:39][N:40]([CH3:41])[C:42]1=[O:43].[F:1][c:2]1[cH:3][c:4]2[c:5]([s:24]1)[C:6]1([O:7][CH2:8][CH2:9]2)[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:13][CH2:14]1.[F:44][c:45]1[c:46]([CH2:47][Br:48])[cH:49][cH:50][cH:51][cH:52]1.[Li+:34].[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([s:24]1)[C:6]1([O:7][CH2:8][CH2:9]2)[CH2:10][CH2:11][N:12]([CH2:15][CH:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:47][c:46]2[c:45]([F:44])[cH:52][cH:51][cH:50][cH:49]2)[CH2:13][CH2:14]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 67968alpha-Bromo-o-fluorotolueneHCID 816462(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 3280088Npc316347HCID 52951553Spiro[piperidine-4,7′-[7H]thieno[2,3-c]pyran]-1-propanoic acid, 2′-fluoro-4′,5′-dihydro-, 1,1-dimethylethyl ester

Product 1

HCID 52951670HCID 52951670, compound

Sources & evidence

ORD record
ord-f03f72f12f234c8a9e90f8f99ab7d0a1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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