Tetrahydrofuran → N-(3-methylisoxazol-5-yl)methoxyphthalimide

HRID 836228Notes

Reaction equation

HRID 836228 reaction equation
[N:40]([C:41]([O:42][CH3:43])=[O:44])=[N:45][C:46]([O:47][CH3:48])=[O:49].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[OH:1][N:2]1[C:3](=[O:12])[c:4]2[c:5]([cH:8][cH:9][cH:10][cH:11]2)[C:6]1=[O:7].[OH:32][CH2:33][c:34]1[cH:35][c:36]([CH3:39])[n:37][o:38]1.[c:13]1([P:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[O:1]([N:2]1[C:3](=[O:12])[c:4]2[c:5]([cH:8][cH:9][cH:10][cH:11]2)[C:6]1=[O:7])[CH2:33][c:34]1[cH:35][c:36]([CH3:39])[n:37][o:38]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 10665N-HydroxyphthalimideHCID 11776TriphenylphosphineHCID 351621Azodicarboxylic acid dimethyl esterHCID 10820493(3-Methylisoxazol-5-yl)methanol

Product 1

HCID 19974982N-(3-methylisoxazol-5-yl)methoxyphthalimide

Sources & evidence

ORD record
ord-264c9471c0244e2e864eee82e2c82e71
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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