Bicarbonate Ion → 2-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

HRID 836636Notes

Reaction equation

HRID 836636 reaction equation
[C:27](=[O:28])([OH:29])[O-:30].[CH3:15][S:16](=[O:17])(=[O:18])[OH:19].[N:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26].[NH2:1][c:2]1[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1.[Na+:31].[OH:9][CH2:10][C:11]([F:12])([F:13])[F:14]>>[c:2]1([O:9][CH2:10][C:11]([F:12])([F:13])[F:14])[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6395Methanesulfonic AcidHCID 64092,2,2-TrifluoroethanolHCID 10906Tert-Butyl nitriteHCID 805282-Chloro-3-pyridylamine

Product 1

HCID 120567282-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

Sources & evidence

ORD record
ord-ab3b2849acd340368d5ca112b2b5b79e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…