Hydrochloric Acid → 1,1-Dimethylethyl N-((4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycinate

HRID 837242Notes

Reaction equation

HRID 837242 reaction equation
[CH2:20]([N:21]([CH:22]([CH3:23])[CH3:24])[CH:25]([CH3:26])[CH3:27])[CH3:28].[CH2:39]1[O:40][CH2:41][CH2:42][O:43][CH2:44]1.[CH3:45][CH2:46][O:47][C:48]([CH3:49])=[O:50].[ClH:29].[NH2:30][CH2:31][C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38].[OH:1][C:2]1=[C:3]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[C:4](=[O:14])[C:5]([CH3:12])([CH3:13])[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21>>[OH:1][C:2]1=[C:3]([C:15](=[O:16])[NH:30][CH2:31][C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[C:4](=[O:14])[C:5]([CH3:12])([CH3:13])[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 151417Glycine tert-butyl esterHCID 57604805Ethyl 1-hydroxy-4,4-dimethyl-3-oxo-3,4-dihydro-2-naphthalenecarboxylate

Product 1

HCID 670997981,1-Dimethylethyl N-((4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycinate

Sources & evidence

ORD record
ord-86112e79c021477ba7d2541ad037ab9e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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