1,2-Dichloroethane → (+/-)-6'-[(3-Chlorobenzoyl)amino]-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione

HRID 837948Notes

Reaction equation

HRID 837948 reaction equation
[CH2:28]([Cl:29])[CH2:30][Cl:31].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[NH2:11][c:12]1[cH:13][c:14]2[c:25]([cH:26][cH:27]1)[CH2:24][C:17]1([CH2:16][CH2:15]2)[NH:18][C:19](=[O:23])[NH:20][C:21]1=[O:22].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][cH:7][c:8]([Cl:9])[cH:10]1.[OH:32][n:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[n:40][n:41]1>>[C:2](=[O:3])([c:4]1[cH:5][cH:6][cH:7][c:8]([Cl:9])[cH:10]1)[NH:11][c:12]1[cH:13][c:14]2[c:25]([cH:26][cH:27]1)[CH2:24][C:17]1([CH2:16][CH2:15]2)[NH:18][C:19](=[O:23])[NH:20][C:21]1=[O:22]

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 4473-Chlorobenzoic AcidHCID 6228DimethylformamideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 184403106'-Amino-3',4'-dihydrospiro[imidazolidine-4,2'(1'H)-naphthalene]-2,5-dione

Product 1

HCID 9820683(+/-)-6'-[(3-Chlorobenzoyl)amino]-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione

Sources & evidence

ORD record
ord-8b11a2d2391842b3932dc5aed5d1c0aa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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