Acetate → 1-(Pyridin-3-yl)piperazine

HRID 838191Notes

Reaction equation

HRID 838191 reaction equation
[Br:7][c:8]1[cH:9][n:10][cH:11][cH:12][cH:13]1.[C:22]([O-:23])(=[O:24])[CH3:25].[C:27]([O-:28])(=[O:29])[CH3:30].[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[CH3:14][c:15]1[c:16]([CH3:17])[cH:18][cH:19][cH:20][cH:21]1.[Pd+2:26].[Pd:31]>>[CH2:1]1[CH2:2][N:3]([c:8]2[cH:9][n:10][cH:11][cH:12][cH:13]2)[CH2:4][CH2:5][NH:6]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 4837PiperazineHCID 7237O-XyleneHCID 122863-BromopyridineHCID 23938PalladiumHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 4372341-(Pyridin-3-yl)piperazine

Sources & evidence

ORD record
ord-3a22b4bad7d2438898014d2c3bfcc42d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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