Hydrochloric Acid → HCID 20133501, compound

HRID 845047Notes

Reaction equation

HRID 845047 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([O:11][CH3:12])[CH:4]=1.Cl[CH2:14][CH2:15][CH2:16][C:17](Cl)=[O:18].[ClH:20]>C1C=CC=CC=1>[CH3:12][O:11][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([O:9][CH3:10])[C:6]=1[C:17]([CH:16]([Cl:20])[CH2:15][CH3:14])=[O:18]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 693011,3,5-TrimethoxybenzeneHCID 783704-Chlorobutyryl chloride

Product 1

HCID 20133501HCID 20133501, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

Over 1 hour 30 min. a solution of 60.5 g (0.232 mole) of stannic chloride in 75 ml of benzene is poured into a solution maintained at about 5° C. of 33.6 g (0.200 mole) of 1,3,5-trimethoxybenzene and of 30.5 g (0.216 mole) of 4-chlorobutyryl chloride in 150 ml of benzene, with agitation for 3 hours at ambient temperature. The reactional medium is poured on to 250 ml of iced 4N hydrochloric acid and the organic phase is decanted.

Workup

  1. customthe organic phase is decanted

Sources & evidence

ORD record
ord-187b3d0c81804794966cb66d37805764
Source dataset
uspto-grants-1988_07
Patent number
US04755522

Reaction notes

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