Benzyl Bromide → HCID 19882341, compound

HRID 847147Notes

Reaction equation

HRID 847147 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15])=[CH:6][CH:5]=1)([O-:3])=[O:2].C(=O)([O-])[O-].[K+].[K+].[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>CC(C)=O>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([S:10][CH2:11][CH2:12][CH2:13][CH2:14][O:15][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 12497321HCID 12497321, compound

Product 1

HCID 19882341HCID 19882341, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

A mixture of 4-(4-nitrophenylthio)-1-butanol (10 mmol) and potassium carbonate (20 mmol) in acetone (100 mL) is treated with a solution of benzylbromide (11 mmol) in acetone (50 mL). When the addition is completed the mixture is heated at reflux temperature for 18 hrs, cooled, filtered, and the filtrate is concentrated to obtain the title compound.

Workup

  1. additionWhen the addition
  2. temperatureis heated
  3. temperatureat reflux temperature for 18 hrs
  4. temperaturecooled
  5. filtrationfiltered
  6. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-3c52e80894a645969fb1530aa7f0e9f3
Source dataset
uspto-grants-1992_08
Patent number
US05140026

Reaction notes

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