反应详情

温度

0 °C

To a solution of N,N'-dimethylhydrazine dihydrochloride (940 mg) and triethylamine (2.15 g) in methylene chloride (30 ml) which was cooled to 0° C., was added isobutyl chloroformate (970 mg). The mixture was stirred at 0° C. for 1 hour. After evaporation of the solvent, the residue was dissolved in ethyl acetate (50 ml) and the solution was washed with 1 M sodium bicarbonate solution and water successively, and dried over sodium sulfate. The solvent was evaporated to give N-isobutoxycarbonyl-N,N'-dimethylhydrazine (922 mg) as an oil.

1. customAfter evaporation of the solvent
2. dissolutionthe residue was dissolved in ethyl acetate (50 ml)
3. washthe solution was washed with 1 M sodium bicarbonate solution and water successively
4. dry with materialdried over sodium sulfate
5. customThe solvent was evaporated