4-Bromobiphenyl → (3''-Nitro-[1,1';4',1'']terphenyl-4''-yl)-carbamic acid tert.-butyl ester

HRID 859281Notes

Reaction equation

HRID 859281 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.Br[C:38]1[CH:43]=[CH:42][C:41]([C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)=[CH:40][CH:39]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:47]2[CH:48]=[CH:49][C:44]([C:41]3[CH:42]=[CH:43][CH:38]=[CH:39][CH:40]=3)=[CH:45][CH:46]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 71014-BromobiphenylHCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Product 1

HCID 69592829(3''-Nitro-[1,1';4',1'']terphenyl-4''-yl)-carbamic acid tert.-butyl ester

Procedure

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 4-bromobiphenyl according to the general procedure C. Obtained as a yellow solid (1.29 g).

Sources & evidence

ORD record
ord-e5169c6bdced4148b56bed1bcf225590
Source dataset
uspto-grants-2006_12
Patent number
US07151098B2

Reaction notes

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