Phenethylamine → HCID 11332776, compound

HRID 862137Notes

Reaction equation

HRID 862137 reaction equation
[CH2:1](CN)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:10](Cl)(=[O:13])[CH:11]=[CH2:12].[CH2:15]([N:17](CC)CC)C>CCOCC>[CH2:1]([N:17]([CH3:15])[C:10](=[O:13])[CH:11]=[CH2:12])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 1001PhenethylamineHCID 8471TriethylamineHCID 13140Acryloyl chloride

Product 1

HCID 11332776HCID 11332776, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A quantity of 121 g of N-benzylmethylamine was reacted with 100 g of acryloyl chloride in the presence of 111 g of triethylamine in ether at 0° C. to 25° C. for 16 hours. The product was filtered, the solvent was removed, and N-benzyl-N-methylacrylamide was isolated in 69% yield by distillation under vacuum Cop 83°-85° C./0.04 mm--Hg).

Workup

  1. filtrationThe product was filtered
  2. customthe solvent was removed

Sources & evidence

ORD record
ord-5d884696b0bb473c86c0aa0f8a85f9ce
Source dataset
uspto-grants-1998_02
Patent number
US05717049

Reaction notes

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