huagongshe.com
HRID863781

反应详情

EQUATION

反应方程式

HRID 863781 的结构方程式

REACTANTS

反应物

3
结构：c1c[nH]cn1
HCID795

Imidazole

C3H4N2

结构：O=Cc1ccccc1O
HCID6998

Salicylaldehyde

C7H6O2

结构：CC(C)(C)[Si](C)(C)Cl
HCID28928

Chloro(1,1-dimethylethyl)dimethylsilane

C6H15ClSi

PRODUCTS

生成物

1
结构：CC(C)(C)[Si](C)(C)Oc1ccccc1C=O
HCID10900635

Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

C13H20O2Si

收率 93%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A solution of 2-hydroxybenzaldehyde (500 mg, 0.44 ml, 4.09 mmol), imidazole (685 mg) and tert-butyldimethylsilyl chloride (680 mg) in DMF is stirred for 24 hours at room temperature. After hydrolysis and customary extraction, chromatography gives 28 (890 mg, 93%).

WORKUP

后处理

  1. customAfter hydrolysis and customary extraction, chromatography