2,6-Dimethoxyphenol → HCID 14886366, compound

HRID 868505Notes

Reaction equation

HRID 868505 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[C:4]=1[OH:11].C1(=O)O[CH2:15][CH2:14][O:13]1.C(=O)([O-])[O-].[K+].[K+]>C1(C)C=CC=CC=1>[CH3:10][O:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[C:4]=1[O:11][CH:14]([OH:13])[CH3:15]

Participants

5

Reactant 3

HCID 70412,6-DimethoxyphenolHCID 7303Ethylene carbonateHCID 11430Potassium Carbonate

Product 1

HCID 14886366HCID 14886366, compoundYield 100.7%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 6.0 g of 2,6-dimethoxyphenol, 6.8 g of ethylene carbonate and 5.4 g of potassium carbonate in 40 ml of toluene was refluxed for 17 hours. After cooling, toluene solution was separated, dried (Na2SO4) and solvent was evaporated. 7.77 g of desired compound was obtained.

Workup

  1. temperaturewas refluxed for 17 hours
  2. temperatureAfter cooling
  3. customtoluene solution was separated
  4. dry with materialdried (Na2SO4) and solvent
  5. customwas evaporated

Sources & evidence

ORD record
ord-6f57dac6ec1f4290a78e514474cafdc2
Source dataset
uspto-grants-1988_10
Patent number
US04780462

Reaction notes

Loading…