Piperidine → 5-[1-(4-Trimethylsilanylethynyl-phenyl)-1H-indol-5-yl]-pent-4-yn-1-ol
Reaction equation
[CH2:30]([CH2:31][CH2:32][C:33]#[CH:34])[OH:35].[CH2:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:7]1[cH:8][cH:9][c:10](-[n:13]2[cH:14][cH:15][c:16]3[cH:17][c:18]([O:22][S:23]([C:24]([F:25])([F:26])[F:27])(=[O:28])=[O:29])[cH:19][cH:20][c:21]23)[cH:11][cH:12]1.[Cu:119][I:120].[Pd:42].[c:100]1([P:101]([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[cH:114][cH:115][cH:116][cH:117][cH:118]1.[c:43]1([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:57][cH:58][cH:59][cH:60][cH:61]1.[c:62]1([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77][cH:78][cH:79][cH:80]1.[c:81]1([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[cH:95][cH:96][cH:97][cH:98][cH:99]1>>[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:7]1[cH:8][cH:9][c:10](-[n:13]2[cH:14][cH:15][c:16]3[cH:17][c:18]([C:34]#[C:33][CH2:32][CH2:31][CH2:30][OH:35])[cH:19][cH:20][c:21]23)[cH:11][cH:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d27504eb5642460b9617d791a5776059
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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