反应详情

温度

82 °C

To a solution of 4 (6.88 g, 28 mmol) in acetonitrile and K2CO3 (6.31 g, 45 mmol) was carefully added benzyl bromide (3.34 mL, 27 mmol). The resulting solution was stirred at 82° C. under reflux overnight. The reaction was stopped by filtration of K2CO3 and the solvent was removed under reduced pressure. The solid obtained was recrystallized from hot hexanes to yield 96% of the product as a white solid.

1. temperatureunder reflux overnight
2. filtrationThe reaction was stopped by filtration of K2CO3
3. customthe solvent was removed under reduced pressure
4. customThe solid obtained
5. customwas recrystallized from hot hexanes