Triethylamine → tert-butyl 4-chloro-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

HRID 87395Notes

Reaction equation

HRID 87395 reaction equation
[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[Cl:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27].[O:53]1[CH2:54][CH2:55][O:56][CH2:57][CH2:58]1.[OH:28][c:29]1[c:30]2[c:31]([n:32][cH:33][n:34]1)[CH2:35][CH2:36][N:37]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:38]2.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[Cl:20][c:29]1[c:30]2[c:31]([n:32][cH:33][n:34]1)[CH2:35][CH2:36][N:37]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:38]2

Participants

6

Reactant 5

HCID 8471TriethylamineHCID 11776TriphenylphosphineHCID 312751,4-DioxaneHCID 31398ChlorosuccinimideHCID 178451656HCID 178451656, compound

Product 1

HCID 56924365tert-butyl 4-chloro-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Sources & evidence

ORD record
ord-09081350d7ab4f56935b57ec27f61a01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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