反应详情

温度

90 °C

1458 g (6.9 mol) of (3-methoxyphenyl)(phenyl)methanone was dissolved in 2090 mL of AcOH. To the solution, 2320 ml (20.6 mol) of 48% HBr was added and the mixture was stirred at 90° C. for 18 hours. The reaction was monitored by TLC (AcOEt:hex 1:9). After reaction was completed the mixture was cooled down to RT and poured into ice with stirring. The precipitated solid was filtered, washed with water and dried yielding the title compound as a white solid (1234 g, 91%).

1. customAfter reaction
2. temperaturewas cooled down to RT
3. additionpoured into ice
4. stirringwith stirring
5. filtrationThe precipitated solid was filtered
6. washwashed with water
7. customdried