Water → HCID 67287223, compound

HRID 879959Notes

Reaction equation

HRID 879959 reaction equation
C(=O)([O-])[O-].[K+].[K+].[CH2:7](I)[CH3:8].[OH:10][C:11]1[CH:20]=[CH:19][C:14]2[S:15][C:16](=[O:18])[O:17][C:13]=2[CH:12]=1.O>CN(C)C=O>[CH2:7]([O:10][C:11]1[CH:20]=[CH:19][C:14]2[S:15][C:16](=[O:18])[O:17][C:13]=2[CH:12]=1)[CH3:8]

Participants

6

Reactant 4

HCID 962WaterHCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 721396-Hydroxy-1,3-benzoxathiol-2-one

Product 1

HCID 67287223HCID 67287223, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Potassium carbonate (533 mg) and ethyl iodide (160 μL) were added to a solution of 6-hydroxy-1,3-benzoxathiol-2-one (336 mg) in N,N-dimethylformamide (10 mL) to form a reaction solution. This reaction solution was stirred for 4 hours at normal temperature. Water was added to the reaction solution. The precipitated crystals were filtered off, thoroughly washed with water and diisopropyl ether, and then dried under reduced pressure to obtain the target product (245 mg) as a colorless solid.

Workup

  1. customto form a reaction solution
  2. filtrationThe precipitated crystals were filtered off
  3. washthoroughly washed with water and diisopropyl ether
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-141e79b990d64d6aa93ad63a6cc641a0
Source dataset
uspto-grants-2015_03
Patent number
US08993543B2

Reaction notes

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